14), most post-14ka individuals from western and central Europe fall close to the WHG cluster and those from eastern Europe close to the EHG cluster, whereas the Tutkaul 1 individual from central Asia falls close to the ANE-related group. Gravettian cranial morphology and human group affinities during the European Upper Palaeolithic. ), no. Interviewed Taiwanese designers and analyzed the interview data. PubMed She supports Propel on the business and marketing side. Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. We further validated the genetic distinction between the Vstonice and Fournol clusters observed in the MDS plot with a series of f4-statistics (Supplementary Data 2.B). But she came up with a way to break down the code and create a website that she was proud of. PubMed The authors declare no competing interests. Rev. Cambridge Archaeol. Ancient human genomes suggest three ancestral populations for present-day Europeans. Reads with a mapping quality below 30 were then filtered with samtools, and the consensus sequences were generated by Schmutzi69. Present-day individuals (gray dots) genotyped on theHumanOrigins dataset are used to define the PCA variation onto which ancient genomes (coloured symbols) are projected. Therefore, as previously reported2, the Vstonice cluster itself results from admixture between western and eastern lineages, which might contribute to the observed homogeneity in cranial morphology among Gravettian-associated individuals22. 4). Join now Sign in . The baseline of each population was determined using the average heterozygosity rate of individuals estimated from pseudo-diploid genotypes (Supplementary Data 1.E). 13). Are you Tina Huang? Ive always liked the idea of using data to make predictions. Details of the grouping and ROH segments are provided in Data S3.B. In no time, she established herself as one of the favorite vloggers of the data community.
I came across her YouTube through Ken Jee. Extended Data Fig. We applied ANGSD 0.93470 and hapCon71 for libraries from male individuals, and applied contamLD72 and a newly developed method that analyses contamination in ROH for female and male libraries (see Supplementary Information, section2 for a detailed description). For phylogenetic reconstruction (Extended Data Fig.
Tina Huang | Chemistry at Illinois 1c). The error bar shows the s.e.m. You have to deal with large datasets; however, you have to do your work in a way that makes sense to your team. Google Scholar. The dates were calibrated using OxCal 4.452 with calibration curve IntCal20 at 95.4% probability53 and when multiple dates were available for the same individual we used the function R_Combine to combine them52. . Nat.
Living up to Expectations: The Strengths and Challenges Experienced by The incoming Villabruna ancestry later became the most widespread hunter-gatherer ancestry across Europe. If youd like to learn more about data science, transitioning into computer science, and software engineering, you can also subscribe to my YouTube channel. Materials provided by Max Planck Institute for Evolutionary Anthropology. received support from the Estonian Research Council grant PUT (PRG243).
Tina Huang - Wikipedia The labels in italic denote previously published individuals without new data generated in this study. Fifth, the Oberkassel ancestry in western and central Europe and the Sidelkino ancestry in eastern Europe remained largely isolated for almost 6,000 years until genetic interactions were first observedaround 8ka in northeastern Germany, possibly associated with cultural exchanges along the Baltics49 and around 7.5ka in the upper Volga region, possibly linked to the spread of pottery in the region50. Nat. Liet. "Presumably, these people came from the Balkans, arrived first in northern Italy around the time of the glacial maximum and spread all the way south to Sicily.". Publications. Check out The data science resume that got me my FAANG job and subscribe to Tina Huangs YouTube channel. Previously, she has interned at Goldman Sachs where she used Python and Scala to implement machine learning techniques for automated anomaly detection. Nowadays, we take it for granted that these features exist, but the integrity of those products is, in fact, a labor of love. Known to have been the coldest phase of the last Ice Age, the LGM is considered to have caused a demographic decline in large parts of Europe10, with populations retracting to southern latitudes as attestedfor exampleby the contemporaneity of the Solutrean culture (2419ka) in the Iberian peninsula and southern France. Save my name, email, and website in this browser for the next time I comment. This channel is about data science, learning, and productivity. Sci. Antonio, M. L. et al. Kotula, A., Piezonka, H. & Tergerger, T. The Mesolithic cemetery of Gro Fredenwalde (north-eastern Germany) and its cultural affiliations.
of Leiden, 2000). Ideally, we also want lots of data because this will give us more confidence in our results. Yang, M. A. et al. Biol. Bilateral trade between China and Russia in 2022 rose 34.3% year-on-year to a record high of 1.28 trillion yuan ($190 billion) in yuan-denominated terms, Chinese customs data showed in early January. No, there are no prerequisites for enrolling. The Gravettian from a palaeodemographic point of view. Our analyses demonstrate that the Fournol cluster is a better source for Magdalenian-associated genomes than Goyet Q116-1. Nature 524, 216219 (2015). Paradis, E., Claude, J. Between 14 and 8ka, all hunter-gatherers in western and central Europe carried only Oberkassel ancestry, with no detectable contribution from the Sidelkino cluster. Surprisingly, the research team found that populations from different regions associated with the Gravettian culture, which was widespread across the European continent between 32,000 and 24,000 years ago, were not closely related to each other. Her motto to live by is "Always minimize effort and maximize outcome!".
Tina_Huang_Resume_i.pdf - Tina Huang hellotinah@gmail.com The sequence alignment/map format and SAMtools. In the video above, she explains the two major components of big data: data warehousing and data science. Commun. Population genomics of Mesolithic Scandinavia: investigating early postglacial migration routes and high-latitude adaptation. However, published Gravettian-associated genomes originate from central and southern Europe, leaving the genetic profile of Gravettian-associated humangroups from western and southwestern Europe undescribed. Billed once. Its the complexity of product development, with all of its moving parts, that makes data immensely powerful. Tina Huang is a recent graduate of Stanford. Sci. In panel a, genetic affinity between different ancestries is indicated by thick lines or shades, while admixture is indicated with arrows. Life During Adulthood: Should One Get Credit Cards? Empirically, the results show that the proposed BERT fine-tuning model with the SRS technique achieves better results. 40, e3 (2012). Nat. Brunel, S. et al. Note: Content may be edited for style and length. Tina has 11 jobs listed on their profile. & Banks, W. E. in Les Socits Gravettiennes du Nord-Ouest Europen: Nouveaux Sites, Nouvelles Donnes, Nouvelles Lectures (eds Touz, O., Goutas, N., Salomon, H. & Noiret, P.) 323266 (Presses Univ. When expanded it provides a list of search options that will switch the search inputs to match the current selection. mtDNA capture63 was also performed for those libraries where mtDNA coverage was not high enough to assess mtDNA haplogroup and contamination. 7 and Supplementary Table 3), which coincides roughly with the first appearance of the Oberkassel ancestry in central Europe. It is often considered as a pan-European cultural mosaic with regional variations in material to symbolic productions20,21. In the box plot the centre line is the median, box bounds delineate the interquartile range and whiskers extend to maximum and minimum values, excluding outliers. Science 360, eaar7711 (2018). I have an undergraduate degree in . Nakatsuka, N. et al. The horizontal dashed line marks the boundary between Late Pleistocene and Holocene. Typically, it calls for a great deal of data heavy-lifting and data visualizations with SQL and Python or R. A number of things can be done with traditional analysis, but it is machine learning that has taken an extremely solid place in product development. 3, 765771 (2019). The length of the colour bar shows the proportion of each ancestry. 5 and Supplementary Information, section9). Sci. Kristen Bell. iScience 25, 104244 (2022). 276, 107319 (2022). Bortolini, E. et al. Genetic sexing revealed 78 maleindividuals and 38 femaleindividuals (Supplementary Fig. Genome-wide patterns of selection in 230 ancient Eurasians. Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry, A genomic Neolithic time transect of hunter-farmer admixture in central Poland, Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America, A genetic history of the pre-contact Caribbean, Ancient genomes from the last three millennia support multiple human dispersals into Wallacea, Ancient DNA reveals admixture history and endogamy in the prehistoric Aegean, A 23,000-year-old southern Iberian individual links human groups that lived in Western Europe before and after the Last Glacial Maximum, Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia, Ancient DNA from mastics solidifies connection between material culture and genetics of mesolithic huntergatherers in Scandinavia, https://github.com/stschiff/sequenceTools, https://reich.hms.harvard.edu/allen-ancient-dna-resource-aadr-downloadable-genotypes-present-day-and-ancient-dna-data, https://edmond.mpdl.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.Y1KJMF, https://haproh.readthedocs.io/en/latest/hapROH_with_contamination.html, https://doi.org/10.1007/978-94-017-7206-8_6, https://doi.org/10.1038/s41559-023-01987-0. Mid and Late Upper Palaeolithic in the Adriatic Basin: chronology, transitions and human adaptations to a changing landscape. 1), we used pathPhynder99 based on the tree from Karmin et al.100. Maier, A. in The Central European Magdalenian 81180 https://doi.org/10.1007/978-94-017-7206-8_6 (Springer, 2015). 6 Reasons We Just Cant Stop. H. Rougier received support from the College of Social and Behavioral Sciences of CSUN and the CSUN Competition for RSCA Awards. YourCourse Certificatehas no expiration date. Tina Huang is a well-known data scientist who has over 10 years of experience on YouTube and has previously worked at a FAANG organization. OUR UNIVERSITY Our University . We also genotyped a selection of previously published individuals with the same approach (Supplementary Data 1.G)2,4,30,74,75,76,77,78.
An ECC-based lightweight remote user authentication - Semantic Scholar This genetic signature is shared among individuals associated with the archaeologically defined Gravettian culture (3326ka) in central and southern Europe and seemingly disappeared after the Last Glacial Maximum4 (LGM). Newsletter, I also have a newsletter called Boop's Keyboard! Sci. These models are easy to implement as well as really helpful in deciding what to build and how much to invest in it. Srie Prhistoire dEurope 9 (ditions, 2001). Trzej niedwiedzi braciszkowie przeywaj swoje dziecistwo, pakujc si w najrozmaitsze tarapaty za spraw magicznego pudeka. An expert in the industry, and a tireless advocate for improving it, Areej AbuAli is an inspiring person for those in the SEO space. @hellotinah. Citations 52. Earlier I had practiced a bit of MySQL, but here through this course I got introduced to PostgreSQL. In her journey of eventually. In particular, the model achieves 96.21% for the validation and 96.47% for testing using the news aggregator data. Contrary to the proposal in Fu et al.4 but in agreement with Petr et al.17, we do not observe a substantial decrease of Neanderthal ancestry in most European hunter-gatherers through time (Supplementary Information, section6 and Supplementary Figs. Thisancestry profile survived during the Last Glacial Maximum (25,000 to 19,000 years ago) in human populations from southwestern Europe associated with the Solutreanculture, and withthe following Magdalenian culturethat re-expanded northeastward after the Last Glacial Maximum. However, the genetic profile of contemporaneous Gravettian-associated individuals from western Europe remains unknown, as is their contribution to populations after the LGM. Curr. A phylogeographic reconstruction of different lineages carrying this ancestry further suggests its entry point into northeastern Italy from the Balkans followed by a north-to-south expansion into the Italian peninsula alongside a population decline through sequential bottlenecks. Other individuals from that period, such as Zlat k from Czechia and UstIshim from Russia, do not carry significantly more Neanderthal ancestry than other non-African groups1,7, indicating differential interactions between Neanderthals and early modern humans during their initial expansions across Eurasia.
The Roger Rabbit's Trousers (1990 film) Credits | JH Movie Collection Within the pipeline, the adapters were removed by AdapterRemoval 2.2.065, reads were mapped with BWA 0.7.12 aln/samse algorithm66, duplications were removed by DeDup 0.12.1 (https://github.com/apeltzer/DeDup) and damage patterns of each library were checked with mapDamage 2.0.6 and 2.0.967. In this video @Tina Huang and I go through 5 subscriber submitted resumes and review them. 2 The distribution of mtDNA and Y-chromosome haplogroups among different hunter-gatherer groups. Connect with them: Email: hellotinah@gmail.com. Ongoing symptoms 3 months after infection by SARS-CoV-2 are well described as long COVID and have become a global health concern [1], [2].Fatigue and dyspnea are the two most common symptoms after infection by SARS-CoV-2 and low physical performance impacting daily activities has been described for up to 6 months after infection [3]. Tina started her YouTube channel in 2020. The libraries underwent shallow shotgun sequencing on an Illumina HiSeq 4000 instrument with 75 single-end-run cycles using the manufacturers protocol, to evaluate the human endogenous DNA content and quality. On the basis of the genetic variation of present-day Europeans, this could imply phenotypic differences between post-14ka hunter-gatherer populations across Europe, with individuals in the Oberkassel cluster possibly exhibiting darker skin and lighter eyes, and individuals in the Sidelkino cluster possibly lighter skin and darker eye colour. Harris, K. & Nielsen, R. The genetic cost of Neanderthal introgression. Proc. Grizz, Panda i Lodomir maj rne charaktery, ale pomimo odmiennoci potrafi wspdziaa i wspiera si w kopotach. Hi! Okenla is also part of Atomicos Angel Programme 2021, and is an advisory board member for both Coders of Colour and the No.10 Innovation Fellowship. In practice, we use machine learning in different conjunctures. Paleogenomic evidence for multi-generational mixing between Neolithic farmers and Mesolithic hunter-gatherers in the Lower Danube Basin. Hi, my name is Tina and I'm a data scientist at a FAANG company. Look here to get updated on my recent favourite books, animes, filming equipment and more! BMC Res. Contrary to West Siberian hunter-gatherers, Tutkaul 1 does not carry an extra eastern Eurasian ancestry, but shows affinity to Iranian Neolithic farmers and some younger populations from Iran and the Turan region (Supplementary Data 2.L). Tina Huang I'm a data scientist, youtuber, and the first Lonely Octopus . The phylogenetic reconstruction of Epigravettian-associated genomes, with Pradis 1 diverging more deeply than all others, indicates that the turnover took place much earlier than 17kathe date of the more derived Tagliente 2 genome. Conversely,additional Oberkassel ancestry is identified in eastern Europe by at least 7.5ka in newly generated genomes from Minino I and Yazykovo from the upper Volga region, whereasa 1,000-years-older individual from Minino I did not have this genetic component. Each bar represents one individual with the ROH grouped in four length categories (grouped by colour). 2023 365 Data Science. Lifetime access to all course materials and updates. 25, 459466 (2015). Hunter-gatherers across the great Adriatic-Po region during the Last Glacial Maximum: environmental and cultural dynamics. Genetic analyses of western European individuals associated with the preceding Badegoulian culture might provide clues on the processes that led to the formation of the GoyetQ2 cluster. El Mirn has a significantly higher similarity to theVillabruna clusterthan Fournol 85 and Le Piage II, while the affinity to theVillabruna cluster in Le Piage II is not significantly higher than in Fournol 85 (Supplementary Data 2.D). Samples with a percentage of human DNA in shotgun data around 0.1% or greater were enriched for a set of 1,237,207 targeted SNPs (1240k capture) across the human genome6. Damgaard, P. et al. The 10 mock interviews provide a great detailed approach to solving any SQL questions. 8). This article reviews qualitative and quantitative studies related to the academic achievement of youth from immigrant Chinese families. Evol. Ontario Institute for Cancer Research Toronto, ON. 15, 22792300 (2020). Biol. Thank you for visiting nature.com. This course will help you build a deliberate strategy when participating in a data scientist job interview involving SQL. 7,794 Followers, 14 Following, 9 Posts - See Instagram photos and videos from Tina Huang (@hellotinah) hellotinah. Its not just the top 200 that this competition attracts, but anyone interested in data science. Jones, E. R. et al. "The data we gained from this study provides us with astonishingly detailed insights into the developments and encounters of West Eurasian hunter-gatherer groups," Posth summarises. Curr. What is Connection Map in Data Visualization? A draft sequence of the Neandertal genome. This secondary analysis of an ongoing adaptive platform trial examines the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. Genome sequence of a 45,000-year-old modern human from western Siberia. Ancient genomes indicate population replacement in Early Neolithic Britain. & Ringbauer, H. hapCon: estimating contamination of ancient genomes by copying from reference haplotypes. 6, 16581668 (2022). Cardiff, Wales, United Kingdom. Ancient Rome: A genetic crossroads of Europe and the Mediterranean. The team analysed the genomes of 356 prehistoric hunter gatherers from different archaeological cultures -- including new data sets of 116 individuals from 14 different European and Central Asian countries.
hellotinah These European regions, therefore, constitute climatic refugia where human populations survived during the LGM. Yu, H. et al.
Imbalanced aspect categorization using bidirectional encoder TV Actress. As recommended, we analysed individuals with over 400,000 SNPs called on the 1240k panel101 and we called ROH longer than 4cM (Supplementary Data 3.B). Quat. Survival of Late Pleistocene hunter-gatherer ancestry in the Iberian Peninsula. Notably, this genetic distinction coincides with dissimilarities in mortuary practice among genetically analysed Gravettian-associated individuals from different parts of Europe. Curr. Taiwan Patent Application M401603, filed 11th April . Early Alpine occupation backdates westward human migration in Late Glacial Europe.
Tina Llorca CPA, CWP, CEPP, CIS, MDRT'S Post - in.linkedin.com 26 and Supplementary Data 2.H). Tina Huang is a data scientist currently working at a large FAANG enterprise. 38. Int. Nat.
How to Become a Data Scientist at FAANG (Ft. Tina Huang) - Morioh All Rights Reserved. Sikora, M. et al. PACEA co-authors of this research benefited from the scientific framework of the University of Bordeauxs IdEx Investments for the Future programme/GPR Human Past. Basically, you minimize effort and maximize outcomes. The bivariate plots show the expansion of Oberkassel and Sidelkino ancestries through time in two European areas (longitude below and above 30 degrees). www.sciencedaily.com/releases/2023/03/230301120846.htm (accessed March 4, 2023). As previously hinted37, we find a large frequency variation in alleles related to skin and eye pigmentation among post-LGM hunter-gatherer groups. Both double-stranded and single-stranded libraries were further amplified with IS5/IS6 primers to reach a concentration of 200400ng/l as measured on a NanoDrop spectrophotometer (Thermo Fisher Scientific). Huang's parents immigrated to New York City where her two older brothers . Charlton, S. et al. Petr, M., Pbo, S., Kelso, J. Ecol. For ds_halfUDG libraries, we called genotypes on all targeted sites from 2bp-masked bam files; for ds_nonUDG libraries, we called genotypes on transversion sites only; for ss_nonUDG libraries, we called genotypes with single-strand mode, which ignores forward reads at C/T polymorphisms and reverse reads at G/A polymorphisms. Sci. 1c and Extended Data Fig. The 3 Greatest Moments in science library uga hours History, Addicted to hills science diet adult small bites? This Villabruna ancestry(hereafter, Villabruna cluster or ancestry) showed connections to ancient and present-day Near Eastern populations4,16, but the mode and tempo of its expansion into the Italian peninsula remain unexplored. In the first place, we have traditional analysis. Genome of Petera Muierii skull shows high diversity and low mutational load in pre-glacial Europe. PubMed Central Tina Huang. Learn with a sense of purpose. In product development, we do lots of opportunity sizing to decide which features to build and what opportunities to invest in. My name is Tina and I'm a data scientist and YouTuber. Modern humans have populated Europe for more than 45,000 years1,2. (grey) of the f4 values estimated from 5cM-block jackknife analysis. Remember, its the problem that defines the tools we use! I Agree, Brandwatch Bulletin #41: 7 Women in Tech You ShouldKnow. The grouping of Epigravettian-associated populations is shown with the same colour in a. Extended Data Fig. Science 328, 710722 (2010). ADS Test cases development, automated test tool design, and validation testing for Alaris' first attachable/detachable infusion pump, which is .
Data Professor - How to Become a Data Scientist at FAANG - Facebook Evol. 1517). Its also hard to predict whats going to happen, but I hope its interesting to people who want to learn more about data science. What is a Pie Chart in Data Visualization? The ancient human specimens analysed in this work derive from multiple scientific collaborations. The youngest individual carrying large portions of hunter-gatherer ancestry in the analysed dataset is from Ostorf in northern Germany, dated to around 5.2ka (>90% Oberkassel clusterplus Sidelkino-clustercomponents)(Supplementary Data 3.F). Tina Huang is very empowering, and she knows what she is talking about. The newly reported individuals with over 15,000 SNPs on the Human Origins dataset are shown in black-outlined and filled symbols, as illustrated in the legend on the right, while representative ancient genomes are shown in outlined symbols, as illustrated in the legend at the bottom of the PCA. The y axis shows the average of calibrated radiocarbon dates in thousands of years (kyr) (Supplementary Data 1.A). Tina's authentic and engaging delivery style allows her to create original content on topics like how to be more productive, how to learn more efficiently, how to land a job in data science . b, Allele frequencies of different hunter-gatherer groups (coloured dots) on four SNPs related to skin colour (SLC24A5 and SLC45A2), eye colour (HERC2/OCA2) and lactase persistence (LCT). F4-statistics further support this view, revealing that Le Piage II is more closely related to the Fournol clusterthan the Vstonice cluster (f4(Mbuti, Le Piage II; Vstonice, Fournol 85)0, Z=6.58). Quat. . Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. Dr. Huang taught General Chemistry, Quantitative Analysis, and Instrumental Methods for eight years at . If material is not included in the articles Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. a, MDS plot of pre-LGM individuals. The pre-40kagroup and theFournol and Vstonice clusters are marked as shaded areas in different colours. You need more data until you have the right ingredients to make a good recipe, but you also need less data until you have the right amount of ingredients to make a bad recipe. The genetic distinction between the Oberkassel and Sidelkino clusters is also clearly noticeable in the diversity of uniparentally inherited markers, as the Oberkassel cluster is dominated by mtDNA haplogroup U5 and Y-chromosome haplogroup I, whereas individuals from the Sidelkino cluster show a higher frequency of mtDNA haplogroups U2, U4 and R1b, and carry uniquely Y-chromosome haplogroups Q, R and J (Extended Data Figs. In article number 2206752, Hao Zeng and co-workers report a soft actuator assembly capable of windassisted dispersal and lift-off/landing action under the control of a light beam.The design is inspired by the seed of dandelion, resembling several biomimetic features, i.e., high porosity, lightweight, and separated vortex ring generation under a steady wind flow. We use cookies to improve your experience and give you personalized content. Ancient admixture in human history. Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-path Neolithic expansion to Western Europe. The ROH segments in hunter-gatherer genomes were identified using hapROH101. The IntCal20 Northern Hemisphere radiocarbon age calibration curve (055 cal kbp). Palma di Cesnola, A. CAS 16, 224 (2015). The data here can also be structured or unstructured. A deft hand at turning dense and complicated topics into informative and entertaining videos, theres a ton to learn from every single video. We built 1 to 8 single- and double-stranded genetic libraries for each individual and enriched them for human DNA on 1.24million single nucleotide polymorphisms6 (SNPs), which were then sequenced and yielded 0.04- to 7.64-fold coverage on average over the targeted SNPs. . Natl Acad. Modern humans began to spread across Eurasia around 45,000 years ago but previous research showed that the first modern humans that arrived in Europe did not contribute to later populations. "It is possible that the migration of early farmers into Europe triggered the retreat of hunter-gatherer populations to the northern edge of Europe. Modern humans have populated Europe for more than 45,000 years 1, 2. We provide five novel insights into the genomic history of hunter-gatherer populations over a time span of 30,000 years from the Upper Palaeolithic to the Neolithic. Check out Do Deepfakes Have Fingerprints? "Ice Age survivors." and D.C. have received funding from the Italian Ministry of University and Research (MUR) PRIN 2017 grants 20177PJ9XF and 20174BTC4R_002. Ecol. Shes the founder of Coding Black Females, a nonprofit with the aim to provide opportunities for Black female developers to develop themselves, meet familiar faces, network, receive support, and build relationships through having regular meetups., Check out the Coding Black Females website. Furthermore, the findings show that there had been no genetic exchange between contemporaneous hunter-gatherer populations in western and eastern Europe for more than 6,000 years.